This talk will focus on current activities and achievements from the Office of Data Science Strategy and highlight the strategic vision of data science at NIH, with emphasis in the areas of artificial intelligence, health informatics, data resources, and computational biosciences.
The treatment paradigm of patients with advanced melanoma has changed drastically with the advent of anti-PD1 based immunotherapy. However, in spite of unprecedented response rates, the fact remains that many patients do not respond to treatment. We will discuss the role of tumor cell metabolism in advanced melanoma, its impact on the tumor microenvironment, and how the tumor microenvironment may be remodled so that more patients can benefit from immunotherapy.
Potentially avoidable hospitalizations of nursing home residents are common and result in increased morbidity, mortality, and excess healthcare expenditures.
Research dollars are increasingly difficult to get, however quality research can be done inexpensively by harnessing existing informational repositories. Research focusing on existing data is especially important in healthcare, where value of care (increasing quality of care at a lower cost) is becoming an important goal for patients, providers, and health plans.