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Sofia Triantafyllou, PhD

Sofia Triantafyllou
  • Adjunct Professor of Biomedical Informatics (2021–Present)
  • Assistant Professor, Department of Mathematics and Applied Mathematics, University of Crete, Greece
  • Affiliated Researcher, Institute of Applied and Computational Mathematics, FORTH

Department of Biomedical Informatics (DBMI) | University of Pittsburgh School of Medicine

Biography

Dr. Sofia Triantafyllou is an Adjunct Professor in the Department of Biomedical Informatics at the University of Pittsburgh School of Medicine, and concurrently an Assistant Professor in the Department of Mathematics and Applied Mathematics at the University of Crete, Greece. She is also an Affiliated Researcher at the Institute of Applied and Computational Mathematics, Foundation for Research and Technology Hellas. Her research focuses on causal discovery, causal effect estimation, and the integration of observational and experimental data for biomedical applications.

Research Interests

Dr. Triantafyllou’s research centers on developing algorithms and methods for causal discovery from heterogeneous data sets, including data arising from multiple overlapping experimental and observational studies. She has contributed foundational work on constraint-based and score-based causal learning, causal Markov boundaries, and the estimation of causal effects from combined data sources. Her applied work spans biological data analysis (mass cytometry, neural recordings) and clinical data including electronic health records.

Specialties

  • Causal Discovery and Causal Inference
  • Bayesian and Graphical Models
  • Machine Learning for Biomedical Data
  • Integration of Observational and Experimental Data
  • Computational Neuroscience

Websites & Links

Education & Training

  • Diploma, Applied Mathematical and Physical SciencesNational Technical University of Athens, Athens, Greece2007
  • M.Sc., Computer ScienceUniversity of Crete, Greece2010
  • Ph.D., Computer ScienceUniversity of Crete, Greece2015
  • Postdoctoral FellowNorthwestern University, Evanston, IL2016–2017
  • Postdoctoral FellowUniversity of Pennsylvania, Philadelphia, PA2017–2018

Representative Publications

  1. Biza K, Tsamardinos I, and Triantafillou S. Out-of-Sample Tuning for Causal Discovery. IEEE Trans Neural Netw Learn Syst, 2022.

  2. Triantafillou S, Saeb S, Lattie EG, Mohr DC, Kording KP. Relationship Between Sleep Quality and Mood: Ecological Momentary Assessment Study. JMIR Ment Health 6(3):e12613, 2019.

  3. Triantafillou S, Lagani V, Heinze-Deml C, et al. Predicting causal relationships from biological data: Applying automated causal discovery on mass cytometry data of human immune cells. Sci Rep 7(1):1–11, 2017.

  4. Triantafillou S, & Tsamardinos I. Constraint-based causal discovery from multiple interventions over overlapping variable sets. J Mach Learn Res 16(1):2147–2205, 2015.

  5. Tsamardinos I, Triantafillou S, & Lagani V. Towards integrative causal analysis of heterogeneous data sets and studies. J Mach Learn Res 13(1):1097–1157, 2012.

Research Grants

Grant / Funding AgencyRoleGrant NumberYears
Individualized Prediction of Treatment Effects Using Data from Both Embedded Clinical Trials and Electronic Health Records
NIH
Co-I2022–Present
Precision Medicine Strategies for Glucocorticoids in Sepsis
NIH
Co-I2021–Present
Developing Artificial Intelligence Literacy
University of Crete
Co-I2023–2024