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Jonathan Arnold, MD

Jonathan Arnold
  • Assistant Professor of Medicine, Division of General Internal Medicine
  • Director of CMI eRecord Initiatives, UPMC
  • Director for Research and Quality Improvement, UPMC McKeesport

Department of Biomedical Informatics (DBMI) | University of Pittsburgh School of Medicine

Biography

Dr. Jonathan Arnold is a practicing general internist and board-certified clinical informaticist at the University of Pittsburgh School of Medicine. He serves as Director of CMI eRecord Initiatives at UPMC and Director for Research and Quality Improvement at UPMC McKeesport. His work focuses on translating real-world EHR data into actionable evidence, designing pragmatic clinical trials, and improving clinical medicine through health informatics.

Research Interests

Dr. Arnold’s research leverages EHR and claims data to generate real-world evidence informing clinical practice. Key areas include the impact of PDMP mandates on opioid prescribing, comparative effectiveness of AI early-warning systems vs. physician judgment for clinical deterioration, real-world outcomes of GLP-1 agonists in type 2 diabetes, EHR-based nudge interventions for high-risk prescribing, lipid-lowering therapy adherence, and long COVID epidemiology through the NIH RECOVER initiative.

Specialties

  • Clinical Informatics
  • Real-World Evidence and EHR-Based Research
  • Clinical Decision Support
  • Pragmatic Clinical Trials

Education & Training

  • B.S.E., Electrical Engineering and Computer ScienceUniversity of Michigan, Ann Arbor, MI1994–1998
  • M.S.E., Computer EngineeringUniversity of Michigan, Ann Arbor, MI1998–2000
  • M.S., Clinical ResearchUniversity of Pittsburgh, Pittsburgh, PA2017–2019
  • M.D.Icahn School of Medicine at Mount Sinai, New York, NY2010–2014
  • Residency, Internal MedicineUPMC, Pittsburgh, PA2014–2017
  • Fellowship, General Internal Medicine Clinical Research (NIH Training Grant)University of Pittsburgh, Pittsburgh, PA2017–2019