Accrual of patients to Clinical Trials (ACT) network

The Accrual of patients to Clinical Trials (ACT) network is a nationwide network of sites that share EHR data to significantly increase participant accrual to the nation’s highest priority clinical trials. It is funded by NCATS' Clinical and Translational Science Awards (CTSA) program that supports efforts to solve system-wide translational research problems to improve the success of U.S. clinical trials. The ACT network is built on existing platforms (i2b2/SHRINE) to create a federated network with common standards, data terminology and shared resources. The ACT investigators are focused on 1) data harmonization across EHR platforms, 2) technical needs assessment and implementation, 3) regulatory approaches to ensure compliance with protocols for data access and participant contact, and 4) governance development to establish proper agreements among institutions. More information is available at NCATS.

This work is funded by grant UL1 TR001857-01S1 from NCATS, NIH.