NIH-funded $14 Million Collaborative Translational Research Consortium among Pitt, Michigan and Wyss Institute

Headline: sciVelo Participates in NIH-funded $14 Million Collaborative Translational Research Consortium among Pitt, Michigan and Wyss Institute to Accelerate Dental, Oral and Craniofacial Research towards Clinical Impact

The University of Pittsburgh, in collaboration with the University of Michigan and the Wyss Institute for Biologically Inspired Engineering, has launched a $14 million initiative to accelerate the translation of promising dental, oral and craniofacial research towards clinical impact with particular emphasis on bridging the “valley of death” between academic research and commercialization.
The Michigan-Pittsburgh-Wyss Resource Center: Supporting Regenerative Medicine in Dental, Oral and Craniofacial Technologies received $11.7 million in National Institutes of Health funding through the National Institute of Dental and Craniofacial Research, as well as funding from institutional sources. One additional resource center at the University of California, San Francisco, was awarded by the NIDCR bringing total funding for this innovative research mechanism to $24 million over three years.
Efforts at the University of Pittsburgh are led by Charles Sfeir, DDS, PhD at the School of Dental Medicine’s Center for Craniofacial Regeneration and William Wagner, PhD at the McGowan Institute for Regenerative Medicine. Pitt brings expertise in translational research having successfully commercialized dozens of regenerative medicine technologies leveraging the product development, manufacturing, pre-clinical assessment, commercialization and regulatory resources available across the University.
The University of Michigan School of Dentistry’s efforts are led by William Giannobile, DDS, MS, DMSc and David Kohn, MSE, PhD. Michigan is the only university that has top-ten dental, medical and engineering schools on a single campus and has significant expertise in dental, oral and craniofacial research and clinical trials.
The Wyss Institute contributes expertise in manufacturing and the fabrication of tissue engineered and regenerative medicine prototypes under the leadership of David Mooney, PhD.
In addition to basic scientific and translational research leadership, the Resource Center leverages several university-based and external partners to create an architecture amenable to rapid commercial translation. Donald P. Taylor, PhD, MBA, Executive Director of sciVelo, Assistant Vice Chancellor for Commercial Translation in the Health Sciences, and Associate Professor of Biomedical Informatics at the University of Pittsburgh, serves as a co-investigator in the Resource Center. “sciVelo will leverage its experience supporting over 200 early-stage University of Pittsburgh translational research projects to provide commercial translation critical path creation for projects supported by the Resource Center.”, stated Dr. Taylor.  
The Resource Center has also partnered with the McGuire Institute, a practice-based research network focused on dental and oral indications to provide clinical needs assessment and validation, as well as The Avenues Company, a dental regenerative product-focused strategic marketing consulting group to provide market needs assessment and validation.
The Resource Center’s architecture for commercial translation acceleration aims to support the initiation of new clinical trials and eventual FDA approval for therapies addressing significant unmet clinical needs in the dental, oral and craniofacial space to increase the impact of academic translational research and industry-based product development.
For more information:
Post Date: 
Wednesday, March 22, 2017