Regularized Tensor Factorization for Multi-Modality Medical Image Classification

Batmanghelich N, Taskar B, Davatzikos C. Regularized Tensor Factorization for Multi-Modality Medical Image Classification. International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI), pp 17-24, 2011. PMID: 22003679

This paper presents a general discriminative dimensionality reduction framework for multi-modal image-based classification in medical imaging datasets. The major goal is to use all modalities simultaneously to transform very high dimensional image to a lower dimensional representation in a discriminative way. In addition to being discriminative, the proposed approach has the advantage of being clinically interpretable. We propose a framework based on regularized tensor decomposition. We show that different variants of tensor factorization imply various hypothesis about data. Inspired by the idea of multi-view dimensionality reduction in machine learning community, two different kinds of tensor decomposition and their implications are presented. We have validated our method on a multi-modal longitudinal brain imaging study. We compared this method with a publically available classification software based on SVM that has shown state-of-the-art classification rate in number of publications.

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2011
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Batmanghelich N, Taskar B, Davatzikos C
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