The MURDOCK Study: a Framingham for the Genomic Era
The study and characterization of disease has traditionally been based upon crude characterization of clinical characteristics, radiographs, and laboratory testing that has evolved over generations. Centered in Kannapolis, NC, the M.U.R.D.O.C.K. Study (Measurement to Understand Reclassification of Disease Of Cabarrus/Kannapolis)is a long-term epidemiological study that aims to segment diseases by combining best-in-class clinical research, statistical, and analytical methods with different omics technologies and electronic health records. In doing so, we will be able to reclassify health and disease and enable the practice of stratified or genomic medicine. In this talk I will present the MURDOCK Study, with an emphasis on the informatics challenges and opportunities it presents.