Dr. Boyce studies the use of informatics and pharmacoepidemiology to support safe and effective medication therapy, especially for older adults. He is currently the principal investigator of a project funded by the National Institute on Aging (K01AG044433) that has the long-term goal of developing an effective informatics intervention that prevents harm to nursing home residents from drug-drug interactions while avoiding known issues with drug-drug interaction alerting such as alert fatigue. He is also the principal investigator of project funded by the National Library of Medicine grant (1R01LM011838-01) to investigate a new paradigm that would reduce preventible medication errors by more effectively synthesizing existing PDDI knowledge, and more rapidly producing evidence to fill in knowledge gaps. He is a co-investigator on a pilot project investigating how to best present clinical pharmacogenomics statements to clinicians and patients. Dr. Boyce was a scholar in the AHRQ-funded University of Pittsburgh Comparative Effectiveness Research Program from 2010-2013. He currently serves as an ad hoc Scientific Merit Reviewer for PCORI and for multiple informatics journals. He co-leads the Knowledge Base Workgroup in the Observational Health Data Sciences and Informatics consortium, and is an invited expert to the Evidence Appraisal Workingroup for the 2013 AHRQ Drug-Drug Interaction Clinical Decision Support Conference Series and the W3C Health Care and Life Sciences Interest group.