Songjian Lu, PhD

Yan G, Chen V, Lu X, Lu S. A signal-based method for finding driver modules of breast cancer metastasis to the lung. Sci Rep. 2017 Aug 30; 7(1):10023. doi: 10.1038/s41598-09951-2. PMID: 28855549. PMC ID: PMC5577160.

Huang T, Kim CK, Alvarez AA, Pangeni RP, Wan X, Song X, Shi T, Yang Y, Sastry N, Horbinski CM, Lu S, Stupp R, Kessler JA, Nishikawa R, Nakano I, Sulman EP, Lu X, James CD, Yin XM, Hu B, Cheng SY. MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma. Cancer Cell. 2017 Dec 11; 32(6):840-855.e8. doi: 10.1016/j.ccell.2017.11.005. PMID: 29232556

S. Lu, C. Cai,  G. Yan,  Z. Zhou, Y. Wan, L. Chen, V. Chen, G. Cooper, L. Obeid, Y. Hannun, A. Lee and X. Lu. Signal-oriented pathway analyses reveal a signaling complex as a synthetic lethal target for p53 mutations, Cancer Research 2016, Minor revision

Lu, S., Mandava, G., Yan, G., and Lu, X (2016) An exact algorithm for finding cancer driver somatic genome alterations: the weighted mutually exclusive maximum set cover problem.  Algorithm for Molecular Biology 11:1, DOI: 10.1186/s13015-016-0073-9   PMCID: PMC4855522

Lu, S., Lu, KN, Cheng, S., Ma, X., Nystrom, N., Lu, X. (2015) Identifying driver genomic alterations in cancers by searching minimum-weight, mutually exclusive sets.  PLoS Computational Biology 11(8):e1004257 PMID: 26317392  PMCID: PMC4552843

Lu, S., Jin, B., Cowart, LA., and Lu, X (2013) From data towards knowledge: Revealing the architecture of signaling systems by unifying knowledge mining and data mining of systematic perturbation data. PLoS One 8(4): e61134  PMID: 23637789 PMCID: PMC3634064

Montefusco DJ, Chen L, Matmati N, Lu S, Newcomb B, Cooper GF, Hannun YA, Lu X. Distinct signaling roles of ceramide species in yeast revealed through systematic perturbation and systems biology analyses.  Science Signaling 6(299), rs14. [DOI: 10.1126/scisignal.2004515] (2013)  PMID: 24170935 PMC3974757

J. Chen, S. Lu. Improved Parameterized Set Splitting Problem: A Probabilistic Approach. Algorithmica. 2009; 54 (4):472-489.

J. Chen, J. Kneis, S. Lu, D. Mölle, S. Richter, P. Rossmanith, S.  Sze, F. Zhang. Randomized divide-and-Conquer: Improved path, matching, and packing algorithm. SIAM Journal on Computing. 2009; 38 (6):2526-2547.

J. Chen, Y. Liu, S. Lu, B. O’Sullivan, I. Razgon. A Fixed-Parameter Algorithm for the Directed Feedback Vertex Set Problem. Journal of the ACM. 2008; 55 (5):21.

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