Rebecca S. Jacobson, MD, MS

Research Interests: 

Dr. Jacobson’s research interests are in the use of natural language processing and deep phenotyping to support personalized medicine and learning health systems. Another area of interest is the use of decision support and feedback methods to increase healthcare quality. Her work is currently funded by two separate U24 grants from the National Cancer Institute.

Professor, Department of Biomedical Informatics,
Director, Biomedical Informatics Graduate Training Program
University of Pittsburgh School of Medicine
Selected Publications: 

Hochheiser, H, Castine, M, Harris, D, Savova, G,  Jacobson, RS, An information model for computable cancer phenotypes. BMC Medical Informatics and Decision Making. Sept. 2016: 1-15. doi=10.1186/s12911-016-0358-4

Hochheiser, H., Ning, Y., Hernandez, A., Horn, J. R., Jacobson, R., & Boyce, R. D. (2016). Using Nonexperts for Annotating Pharmacokinetic Drug-Drug Interaction Mentions in Product Labeling: A Feasibility Study. JMIR Research Protocols, 5(2), e40. PMID: 27066806 PMCID: PMC4844909

Tseytlin E, Mitchell K, Legowski E, Corrigan J, Chavan G, Jacobson RS. NOBLE – Flexible concept recognition for large-scale biomedical natural language processing. BMC Bioinformatics 2016 17:32. PMID: 26763894 [PubMed - in process]  PMCID:  PMC4712516

Jacobson RS, Becich MJ, Bollag RJ, Chavan G, Dhir R, Corrigan J, Feldman M, Ganguly A, Gaudioso C, Legowski E, Maihle N, Mitchell K, Murphy M, Sakthivel M, Tseytlin E, Weaver J.  A Federated Network for Translational Cancer Research Using Clinical Data and Biospecimens.  Cancer Research 2015;75(24):5194-201. PMID:26670560 PMCID:PMC4683415 [Available on 2016-12-15]

Cooper GF, Bahar I, Becich MJ, Benos PV, Berg J, Espino JU, Jacobson RC, Kienholz M, Lee AV, Lu X, Scheines R, Center for Causal Discovery team. The Center for causal discovery of biomedical knowledge from Big Data. Journal of the American Medical Informatics Association 2015 Jul 2. pii: ocv059. doi: 10.1093/jamia/ocv059. [Epub ahead of print]  PMID: 26138794

Haendel, M. A., Vasilevsky, N., Brush, M., Hochheiser, H. S., Jacobsen, J., Oellrich, A., … Smedley, D. (2015). Disease insights through cross-species phenotype comparisons. Mammalian Genome, 26(9-10), 548–555.  PMID: 26092691  PMCID: PMC4602072

Geskin A, Legowski E, Chakka A, Chandran UR, Barmada MM, LaFramboise WA, Berg J, Jacobson RS. (2015). Needs Assessment for Research Use of High-Throughput Sequencing at a Large Academic Medical Center. PLoS ONE, 10(6), e0131166. PMID: 26115441 PMCID: PMC4483235

Landis-Lewis, Z., Brehaut, J. C., Hochheiser, H., Douglas, G. P., & Jacobson, R. S. (2015). Computer-supported feedback message tailoring: theory-informed adaptation of clinical audit and feedback for learning and behavior change. Implementation Science, 10(1), 1.

Liu K, Mitchell KJ, Chapman WW, Savova GK, Sioutos N, Ruben DL, Crowley RS. Formative Evaluation of Ontology Learning Methods by Using Existing Ontologies as Reference Standards. Methods of Information in Medicine, 2013 May 13;52(4). PMID: 23666409 [PubMed - in process]

Kuqi K, Eveleigh T, Holzer T, Sarkani S, Crowley RS. Redesigning Electronic Medical Record User Interfaces: A Matrix-Based Framework for Improving Usability J Healthc Eng. 2013;4(3):427-52. doi: 10.1260/2040-2295.4.3.427 PMID: 23965597 [PubMed in process]

Zheng J, Chapman WW, Miller TA, Chen L, Crowley RS, Savova GK. A system for coreference resolution for the clinical narrative. J Am Med Inform Assoc. 2012 Jul 1;19(4):660-7. Epub 2012 Jan 31. PMCID: PMC3384116 [Available on 2013/7/1]

Crowley RS, Legowski E, Medvedeva O, Reitmeyer K, Tseytlin E, Castine M, Jukic D, Mello-Thoms C. Automated detection of heuristics and biases among pathologists in a computer-based system. Adv in Health Sci Educ, Theory and Practice, Epub ahead of print, May 29, 2012. PMID:22618855

Landis Lewis Z, Mello-Thoms C, Gadabu OJ, Gillespie M, Douglas GP, Crowley RS. The Feasibility of Automating Audit and Feedback for ART Guideline Adherence in Malawi. J Am Med Inform Assoc. 2011 Nov-Dec;18(6):868-74. Epub 2011 May 12. PMCID: PMC3197989

Lui K, Hogan WR, Crowley RS. Natural Language Processing Methods and Systems for Biomedical Ontology Learning. J Biomed Inform. 2010 Jul 17. [Epub ahead of print] PMID: 20647054 [PubMed—in process]

Crowley RS, Gryzbicki D, Legowski E, Wagner L, Castine M, Medvedeva O, Tseytlin E, Jukic D, Raab S.  Use of a Medical ITS Improves Reporting Performance among Community Pathologists. Tenth International Conference on Intelligent Tutoring Systems: Bridges to Learning (ITS 2010), Carnegie Mellon University, Pittsburgh PA, June 14-18, 2010.

Crowley RS, Castine M, Mitchell KJ, Chavan G, McSherry T, Feldman M.  caTIES - A Grid Based System for Coding and Retrieval of Surgical Pathology Reports and Tissue Specimens In Support Of Translational Research. J Am Med Inform Assoc. 2010 May 1;17(3):253-64  PMID: 20442142 [PubMed—in process]

Bartos CE, Butler BS, Crowley RS, Ranked Levels of Influence Model: Selecting Influence Techniques to Minimize IT Resistance. J Biomed Inform. 2010 Apr. [Epub ahead of print].PMID: 20176135

Landis Lewis Z, Douglas G, Monaco V, Crowley RS, Touchscreen Task Efficiency and Learnability in an Electronic Medical Record at the Point-of-Care. 13th World Congress on Medical and Health Informatics Medinfo 2010, Cape Town, South Africa, 12-15th September 2010 (Accepted February 2010, Nominated for Best Student Paper, June 2010).  PMID: 20841658