Harry Hochheiser, PhD

Room 519
5607 Baum Boulevard
Pittsburgh, PA 15206
PA
412-648-9300
412-624-5310
harryhochheiser
Admin Support: 
Primary Appointment: 
Assistant Professor, Department of Biomedical Informatics
Assistant Professor in the Intelligent Systems Program
Associate Director, Biomedical Informatics Training Program
University of Pittsburgh School of Medicine
Peer-reviewed Publications: 
43
Biography
My research has covered a range of topics, including human-computer interaction, information visualization, bioinformatics, universal usability, security, privacy, and public policy implications of computing systems. I have published more than 25 peer-reviewed journal and conference papers and two book chapters. I am currently working on the development of highly-interactive, user-centered systems for finding and exploring biomedical datasets, with specific applications ranging from basic research data to electronic health records. Earlier efforts included NSF-funded projects in computer security in introductory computer science classes and computational thinking. In addition to my research experience in computer science education, I have taught and developed several courses at both undergraduate and graduate levels, including Introductory Computer Science, Introduction to Algorithms, Information Visualization, Advanced Web Development, and Human-Computer Interaction. I am a reviewer for several journals, including Information Visualization, ACM Transactions on Human Computer Interaction, Interacting with Computers, Risk Analysis, and Advances in Bioinformatics. I have also served on program committees for several conferences, including the IEEE Information Visualization Symposium (2007-2009), the ACM Symposium on Usable Privacy and Security (2009-2010), Advanced Visual Interfaces (2010), and the Security and Privacy in Medical and Home-Care Systems Workshop (2009-2010). I have been a member of the Executive Committee of the Association of Computing Machinery's US Public Policy Committee (USACM) since 2004, and I am co-author of Research Methods in Human-Computer Interaction (Wiley, 2010).
Research/Scholarship Interests: 
biomedical informatics; bioinformatics; clinical informatics; collaborative science; human-computer interaction; information visualization; computer-supported cooperative work; Attitude of Health Personnel; Humans; Workflow; Young Adult; Aged; Adult; Nursing Methodology Research; Qualitative Research; Nursing Staff, Hospital; Health Insurance Portability and Accountability Act; Nursing Evaluation Research; Point-of-Care Systems; United States; Male; Electronic Health Records; Nursing Records; Middle Aged
(Legend: Current Major/ Current Minor, Non-current Major/ Non-current Minor)
Education & Training: 
Post-Doctoral Computational Biology National Institute on Aging in 2006
PhD Computer Science University of Maryland in 2003
MS Electrical Engineering and Computer Science Massachusetts Institute of Technology in 1991
BS Computer Science and Engineering Massachusetts Institute of Technology in 1991
Academic Appointments: 
2012 - present
Assistant Professor, Intelligent Systems Program, Kenneth P. Dietrich School of Arts and Sciences, University of Pittsburgh
2009 - present
Assistant Professor, Biomedical Informatics, Medicine, University of Pittsburgh
Grants & Contracts: 
09/15/2015 - 06/30/2019
NLM 1 R01 LM012095
Development and Evaluation of a Learning Electronic Medical Record System
Role: Co-Investigator
09/15/2014 - 08/31/2018
NHGRI U54HG008540
Center for Causal Modeling and Discovery of Biomedical Knowledge from Big Data
Role: Co-Investigator
08/1/2014 - 07/31/2015
NIH R24OD011883
Supplement to Supplement to Semantic LAMHDI: Linking diseases to model organism resources
Role: Co-Investigator
05/1/2014 - 04/30/2019
NIH/NCI 1 U24 CA184407-01
Cancer Deep Phenotype Extraction from Electronic Medical Records
Role: Co-Investigator
05/1/2014 - 04/30/2019
NIH 1U01DE024425-01
Human Genomics Analysis Interface for FaceBase 2
Role: Co-Investigator
02/1/2014 - 02/1/2018
Baobab Health Trust (CDC) U2GGH00729
Improving the delivery & management of HIV /AIDS care in Malawi through Appropriate Medical Informatics
Role: Co-Investigator
02/1/2014 - 01/31/2017
NIH/NLM 1 R01 LM011838-01
Addressing gaps in clinically useful evidence on drug-drug interactions
Role: Co-Investigator
09/1/2012 - 06/30/2016
Oregon Health Sciences University (NIH) 1R24 OD011883
Semantic LAMHDI: Linking diseases to model organism resources
Role: Co-Investigator
07/1/2012 - 06/30/2016
AHRQ 5R01HS021290
Quantifying Electronic Medical Records Usability to Improve Clinical Workflow
Role: Co-Investigator
04/1/2012 - 03/31/2014
DHHS 90TR0002-01
SHARP Area 4: Secondary Use of EHR Data
Role: Co-Investigator
04/1/2012 - 03/31/2015
NIH 1U01HL112707
Sarcoidosis and A1AT Genomics & Informatics Center
Role: Co-Investigator
09/9/2011 - 04/30/2014
NIH 3U01DE020050-03S1
Ontology-based integration of human studies data
Role: Co-Investigator
07/1/2011 - 08/31/2015
NIH 1R01LM010964
Interactive Search and Review of Clinical Records with Multi-layered Semantic Annotation
Role: Co-Investigator
09/21/2009 - 04/30/2014
University of Iowa (NIH) 5 U01 DE020057-04
FaceBase Data Management and Coordination Hub
Role: Co-Investigator

 

Publications

Jonathan Lazar, Julio Abascal, Simone Barbosa, Jeremy Barksdale, Batya Friedman, Jens Grossklags, Jan Gulliksen, Jeff Johnson, Tom McEwan, Loïc Martínez-Normand, Wibke Michalk, Janice Tsai, Gerrit van der Veer, Hans von Axelson, Ake Walldius, Gill Whitney, Marco Winckler, Volker Wulf, Elizabeth F. Churchill, Lorrie Cranor, Janet Davis, Alan Hedge, Harry Hochheiser, Juan Pablo Hourcade, Clayton Lewis, Lisa Nathan, Fabio Paterno, Blake Reid, Whitney Quesenbery, Ted Selker and Brian Wentz (2016), "Human–Computer Interaction and International Public Policymaking: A Framework for Understanding and Taking Future Actions", Foundations and Trends® Human–Computer Interaction: Vol. 9: No. 2, pp 69-149. http://dx.doi.org/10.1561/1100000062

McMurry JA, Köhler S, Washington NL, Balhoff JP, Borromeo C, Brush M, Carbon S, Conlin T, Dunn N, Engelstad M, Foster E, Gourdine JP, Jacobsen JO, Keith D, Laraway B, Xuan JN, Shefchek K, Vasilevsky NA, Yuan Z, Lewis SE, Hochheiser H, Groza T, Smedley D, Robinson PN, Mungall CJ, Haendel MA. Navigating the Phenotype Frontier: The Monarch Initiative. Genetics. 2016 Aug;203(4):1491-5. PMID: 27516611 PMCID: PMC4981258 [Available on 2017-08-01]

Hochheiser, H., Ning, Y., Hernandez, A., Horn, J. R., Jacobson, R., & Boyce, R. D. (2016). Using Nonexperts for Annotating Pharmacokinetic Drug-Drug Interaction Mentions in Product Labeling: A Feasibility Study. JMIR Research Protocols, 5(2), e40. http://doi.org/10.2196/resprot.5028 PMID: 27066806 PMCID: PMC4844909

Cooper GF, Bahar I, Becich MJ, Benos PV, Berg J, Espino JU, Jacobson RC, Kienholz M, Lee AV, Lu X, Scheines R, Center for Causal Discovery team. The Center for causal discovery of biomedical knowledge from Big Data. Journal of the American Medical Informatics Association 2015 Jul 2. pii: ocv059. doi: 10.1093/jamia/ocv059. [Epub ahead of print]  PMID: 26138794

King AJ, Cooper GF, Hochheiser H, Clermont G. Development and preliminary evaluation of a prototype of a learning electronic medical record system. In: Proceedings of the Symposium of the American Medical Informatics Association, (2015) Nov 5;2015:1967-75 PMID: 26958296 PMCID: PMC4765593

Landis-Lewis, Z., Brehaut, J. C., Hochheiser, H., Douglas, G. P., & Jacobson, R. S. (2015). Computer-supported feedback message tailoring: theory-informed adaptation of clinical audit and feedback for learning and behavior change. Implementation Science, 10(1), 1.

Haendel, M. A., Vasilevsky, N., Brush, M., Hochheiser, H. S., Jacobsen, J., Oellrich, A., … Smedley, D. (2015). Disease insights through cross-species phenotype comparisons. Mammalian Genome, 26(9-10), 548–555. http://doi.org/10.1007/s00335-015-9577-8  PMID: 26092691  PMCID: PMC4602072

Mungall, C. J., Washington, N. L., Nguyen-Xuan, J., Condit, C., Smedley, D., Köhler, S., Groza, T., Shefchek, K., Hochheiser, H., Robinson, P. N., Lewis, S. E. and Haendel, M. A. (2015), Use of Model Organism and Disease Databases to Support Matchmaking for Human Disease Gene Discovery. Human Mutation, 36: 979–984. doi:10.1002/humu.22857  PMID:  26269093

Landis-Lewis, Z., Douglas, G. P., Hochheiser, H., Kam, M., Gadabu, O., Bwanali, M., & Jacobson, R. S. (2015). Computer-Supported Feedback Message Tailoring for Healthcare Providers in Malawi: Proof-of-Concept. AMIA Annual Symposium Proceedings, 2015, 814–823.

Borromeo CD, Schleyer TK, Becich MJ, Hochheiser H.  Finding Collaborators: Toward Interactive Discovery Tools for Research Network Systems. J Med Internet Res 2014;16(11):e244 DOI: 10.2196/jmir.3444 PMID: 25370463

Ayvaz, S., Zhu, Q., Hochheiser, H., Brochhausen, M., Horn, J., Dumontier, M., … Boyce, R. D. (2014). Drug-Drug Interaction Data Source Survey and Linking. AMIA Summits on Translational Science Proceedings, 2014, 16. PMID: 25717393 PMCID: PMC4333686

Ligons, F. M., Mello-Thoms, C., Handler, S. M., Romagnoli, K. M., & Hochheiser, H. (2014). Assessing the impact of cognitive impairment on the usability of an electronic medication delivery unit in an assisted living population. International Journal of Medical Informatics, 83(11), 841–848. http://doi.org/10.1016/j.ijmedinf.2014.07.004 PMID: 25153770 PMCID: PMC4268135

Pages

Dr. Hochheiser’s research focuses on the design of usable systems for use in clinical and research settings. He is particularly interested in using user-centered design techniques to inform the design of highly-interactive information visualization systems for the interpretation of complex data sets in domains such as bioinformatics and health care. Dr. Hochheiser is currently working on the development of user-centered tools for annotating, searching, and browsing of biomedical data in online repositories. As part of the FaceBase (www.facebase.org) project, he is working on the design, implementation, and evaluation of highly-interactive tools for exploring genomic, genetic, demographic, and phenotypic data sets from craniofacial research, with ultimate goal of developing tools and techniques that can be applied to a other domains.

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