Department of Biomedical Informatics

Profile

William A. Laframboise, PhD

Associate Professor of Pathology

Assistant Professor of Biomedical Informatics

Contact Info:

5230 Centre Avenue
West Wing WG21.3

Phone: (412) 623-6160
E-mail: laframboisewa@upmc.edu

Publications

LaFramboise WA, Bombach KL, Pogozelski AR, Cullen RF, Muha N, Lyons-Weiler J, Spear S, Dhir RJ Guthrie RD, Magovern JA. Hepatic Gene Expression Response to Acute Indomethacin Exposure. Mol Diagn.Ther. 2006 10: 187-196.

Ma C, Lyons-Weiler M, Liang W, LaFramboise WA, Gilbertson JR, Becich MJ, Monzon FA. In vitro Transcription, Amplification and Labeling Methods Contribute to the Variability of Gene Expression Profiling with DNA Microarrays. J Mol Diagn. 2006 Vol. 8, No. 2, 183-192

Singh MK, Scott TF, LaFramboise WA, Hu FZ, Post JC, Ehrlich GD. Gene expression changes in peripheral blood mononuclear cells from multiple sclerosis patients undergoing beta-interferon therapy. J Neurol Sci. 2007 Jul 15;258(1-2):52-9. Epub 2007 Apr 30.

LaFramboise WA, Scalise D, Stoodley P, Graner SR, Guthrie RD, Magovern JA, Becich MJ. Cardiac fibroblasts influence cardiomyocyte phenotype in vitro. Am J Physiol Cell Physiol. 2007 May;292(5):C1799-808. Epub 2007 Jan 17.

Research Funding

P01 CA 10194401A2 (Lotze)
Integrating NK and DC into Cancer Therapy
Role/Effort: Co-Inventigator 2%
Years Inclusive: 07/01/2007 06/30/2008
Source: NCI

W81XWH-05-2-0066(Becich)
Proteomics and Bioinformatics Core Facilities
Role/Effort: Co-Investigator 98%
Years Inclusive: 07/01/07-06/30/09
Source: USAMRAA Prime Award (TATRC)