Assistant Professor of Biomedical Informatics

Assistant Professor of Intelligent Systems

Contact Info:

Research Interests

Madhavi Ganapathiraju holds an M.Engg degree in Electrical and Communications Engineering from Indian Institute of Science and a Ph.D. in Language and Information Technologies from Carnegie Mellon University. Her Ph.D. thesis focus was on the application of signal processing and language processing methods to the study of protein and proteome sequences, which led to the development of novel algorithms that have been applied widely to biological sequence analyses. Her current research focus is in the area of machine learning and algorithm development for computational and predictive biomedicine. She is inclined towards development of algorithms enriched with multidisciplinary approaches.

Education

• India Institute of Science, India, M.Engg., Electrical Communications Engineering, 1998
• Carnegie Mellon University, Pittsburgh, PA, PhD, Computer Science, 2007

Publications

Computational Biology

Ganapathiraju M, Balakrishnan N, Reddy R, Klein-Seetharaman J. Transmembrane helix prediction using amino acid property features and latent semantic analysis. BMC Bioinformatics. 2008;9 Suppl 1:S4. PMID: 18315857

Ganapathiraju M, Jursa CJ, Karimi HA, Klein-Seetharaman J. TMpro web server and web service: transmembrane helix prediction through amino acid property analysis. Bioinformatics. 2007 Oct 15;23(20):2795-6. Epub 2007 Aug 27. PMID: 17724062

Poddar A, Chandra N, Ganapathiraju M, Sekar K, Klein-Seetharaman J, Reddy R, Balakrishnan N. Evolutionary insights from suffix array-based genome sequence analysis. J Biosci. 2007 Aug;32(5):871-81. PMID: 17724062

Tastan O, Yu E, Ganapathiraju M, Aref A, Rader AJ, Klein-Seetharaman J. Comparison of stability predictions and simulated unfolding of rhodopsin structures. Photochem Photobiol. 2007 Mar-Apr;83(2):351-62. PMID: 17576347

Iannaccone A, Man D, Waseem N, Jennings BJ, Ganapathiraju M, Gallaher K, Reese E, Bhattacharya SS, Klein-Seetharaman J. Retinitis pigmentosa associated with rhodopsin mutations: Correlation between phenotypic variability and molecular effects. Vision Res. 2006 Dec;46(27):4556-67. Epub 2006 Oct 2. PMID: 17014888

Ganapathiraju M, Manoharan V, Klein-Seetharaman J. BLMT: statistical sequence analysis using N-grams. Appl Bioinformatics. 2004;3(2-3):193-200. PMID: 15693744

“Collaborative Discovery and Biological Language Modeling Interface”, Madhavi Ganapathiraju, Vijayalaxmi Manoharan, Raj Reddy and Judith Klein-Seetharaman, Lecture Notes in Artificial Intelligence, LNCS/LNAI 3864, 2006.

“Computational Biology and Language”, Madhavi Ganapathiraju, N. Balakrishnan, Raj Reddy and Judith Klein-Seetharaman, Lecture Notes in Artificial Intelligence, LNCS/LNAI 3345, 2004.

“Characterization of Protein Secondary Structure using Latent Semantic Analysis”, Madhavi Ganapathiraju, Judith Klein-Seetharaman, N. Balakrishnan and Raj Reddy, IEEE Signal Processing Magazine, vol. 21, issue 3, May 2004.

Digital Library and Indian Language Processing

“Digital Library of India: a testbed for Indian language research”, N. Balakrishnan, Raj Reddy, Madhavi Ganapathiraju, Vamshi Ambati, IEEE Technical Committee on Digital Libraries (TCDL) Bulletin, vol 3, issue 1, 2006.

“Om: One tool for many (Indian) languages”, Ganapathiraju Madhavi, Balakrishnan Mini, Balakrishnan N., Reddy Raj, Journal of Zhejiang University SCIENCE, Vol 6A, No. 11, pp 1348-1353, Oct 2005.

“Improving Recognition Accuracy on CVSD speech in mismatched conditions”, Madhavi Ganapathiraju, N. Balakrishnan and Raj Reddy, WSEAS Transactions on Computers, Vol 2, Issue 4, October 2003.

Key Personnel

Yolanda DiBucci - Administrative Support yodi@pitt.edu

Graduated Students

Asia D. Mitchell - Certificate Student (DBMI)
Thahir P. Mohamed - M.S. Student (ISP)